Assuming the Orange aren't the first 1-seed to lose their first game of the Dance, SU would then face the winner of Kansas St. and Southern Miss. The next top three seeds in the East are Ohio State, Florida State and Wisconsin.
St. Bonaventure is also in the East Region, but the Bonnies will play their first round game in Nashville. Bonaventure is a 14-seed and will face Florida State in the first round.
If Syracuse or St. Bonaventure make the Sweet 16, the next two games will be played in Boston the following Thursday and Saturday.
Prescott Rossi is in Syracuse talking with the Orange about their spot in the bracket. You can see reaction in this spot later tonight or on TV at 10pm on Fox Rochester or at 11pm on News 8.